THE RELATIONSHIP OF SOME INDICATORS OF INSULIN RESISTANCE WITH AGE IN PATIENTS SUFFERING FROM CHRONIC KIDNEY DISEASE

Authors

  • N.U. Kayumov

Keywords:

chronic kidney disease, correlation, glucose, glycosylated hemoglobin, insulin, NOME index.

Abstract

One hundred seventeen patients aged 20-69 years with stage 2-4 chronic kidney disease were examined. All patients were divided into three subgroups: 20-39 years old, 40-59 years old and 60-69 years old.  Among them, correlations between the age of patients and the levels of fasting glycemia, glycosylated hemoglobin, immunoreactive insulin, and the NOME index were studied. The diagnosis of chronic kidney disease was established by the glomerular filtration rate in accordance with the KDIGO criteria. In general, among the entire group of patients included in the study (117 people), positive and reliable associations of age with all the studied indicators were revealed. However, in the subgroups, the correlation indicators had significant differences.

References

Centers for Disease Control and Prevention. Chronic Kidney Disease in the United States, 2023. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention; 2023. https://www.cdc.gov/kidneydisease/publications-resources/CKD-national-facts.html

Smirnov A.V., Dobronravov I.G, Kayukov A.SH. i dr. Epidemiologiya i social'no-ekonomicheskie aspekty hronicheskoj bolezni pochek. Nefrologiya. – 2006. – T.10, № 1. – S.7-12.

Rutkowski B. Chahging patient of endstage renal disease in Central and Eastern Europe. Nephrol. Dial. Transplant. – 2000. – Vol. 15. – Р.156-160.

Claire A. Lawson, Wan Ting Tay, Lizelle Bernhardt, et al. Association Between Diabetes, Chronic Kidney Disease, and Outcomes in People With Heart Failure From Asia, JACC: Asia, Volume 3, Issue 4, 2023, Pages 611-621, ISSN 2772-3747, https://doi.org/10.1016/j.jacasi.2023.03.005.

Cem Tanriover, Sidar Copur, Ali Mutlu, et al. Early aging and premature vascular aging in chronic kidney disease, Clinical Kidney Journal, Volume 16, Issue 11, November 2023, Pages 1751–1765, https://doi.org/10.1093/ckj/sfad076

Kayumov U.K. Izuchenie nekotoryh vnutrennih boleznej pri metabolicheskom sindrome i razlichnyh kategoriyah giperglikemii. Evrazijskij nauchnyj zhurnal. – 2017. - № 2. – S. 405-408. http://journalpro.ru/articles/izuchenie-nekotorykh-vnutrennikh-bolezney-pri-metabolicheskom-sindrome-i-razlichnykh-kategoriyakh-gi/

Kim, S., Kim, G. & Kim, J.H. Additive interaction of diabetes mellitus and chronic kidney disease in cancer patient mortality risk. Sci Rep 12, 19957 (2022). https://doi.org/10.1038/s41598-022-24466-1

Published

2023-11-01